Case reports

Growing teratoma syndrome: A case report and review of the literature

Anuja Abraham, Abraham Peedicayil, Anitha Thomas, Rachel Chandy, Beena Kingsbury


A rare case of growing teratoma syndrome (GTS) of the ovary is presented, with a review of the literature. A 36-year-old woman had 6 months’ duration of back pain and abdominal fullness. She had undergone surgery elsewhere (right salpingo-oophorectomy) followed by chemotherapy for a histopathologically diagnosed immature teratoma of the right ovary 6 years previously. Imaging showed evidence of extensive peritoneal cystic metastases indenting the liver and in the pelvis and right suprarenal region. As tumour markers were within the normal range, a diagnosis of GTS was made. The patient underwent explorative laparotomy with total hysterectomy and left salpingo-oophorectomy, and debulking of peritoneal deposits. Histopathological examination identified mature cystic teratoma. The available literature on this condition, with definitions, understanding of the pathophysiology and prognosis, is reviewed.

Authors' affiliations

Anuja Abraham, Christian Medical College, Vellore, India

Abraham Peedicayil, Christian Medical College, Vellore, India

Anitha Thomas, Christian Medical College, Vellore, India

Rachel Chandy, Christian Medical College, Vellore, India

Beena Kingsbury, Christian Medical College, Vellore, India

Full Text



Teratoma; Chemotherapeutic retroconversion

Cite this article

South African Journal of Obstetrics and Gynaecology 2014;20(3):93-94. DOI:10.7196/sajog.794

Article History

Date submitted: 2013-09-27
Date published: 2014-10-23

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