Case reports

Successful pregnancy in a patient with Swyer syndrome, or pure 46,XY gonadal dysgenesis

A chrysostomou, M Tsuari


Swyer syndrome, or pure 46,XY gonadal dysgenesis, is a rare disorder of sex development, characterised by the failure of sex gland development (ovaries or testes) in a phenotypic female patient. A 24-year-old woman with this syndrome presented at a tertiary academic hospital in South Africa, complaining of primary amenorrhoea and infertility. After gonadectomy and fertility treatment, a rare successful pregnancy outcome was achieved. A patient with Swyer syndrome, in a specialist fertility programme, can maintain a normal pregnancy and delivery.

Authors' affiliations

A chrysostomou, Department of Obstetrics and Gynaecology, Charlotte Maxeke Johannesburg Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

M Tsuari, Netcare Linkwood Hospital, Johannesburg, South Africa

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Swyer Syndrome; Infertility; Amenorrhoea;

Cite this article

South African Journal of Obstetrics and Gynaecology 2019;25(1):9. DOI:10.7196/sajog.1448

Article History

Date submitted: 2019-03-15
Date published: 2019-08-27

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